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SKU: 005ASF

Human Liver S9 Fraction-50 Donors (0.5 mL)

Subcellular Fractions > Liver S9 Fractions

Product Type: SubCellsular Fractions

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Liver

$1,249.00
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Cell Name: Human Liver S9 Fraction-50 Donors (0.5 mL)

  • Description
    Pooled Human Liver S9 Fractions provide a fully characterized, relevant, reliable and reproducible in vitro tool. Pooled Liver S9 Fractions from pools of 50 donors gives an accurate and economic method of deriving a population representation that may be sed to describe the metabolic profile of a drug or drug candidate in high-throughput assays as well as the following other uses:
    Conduct studies of metabolic stability (% of original drug remaining over time)
    Identify which cytochrome P450 (CYP) enzymes oxidize a drug candidate and which UDP-glucuronosyltransferase (UGT) enzymes are responsible for glucuronidation
    Identify, quantify and characterize drug metabolites
    Describe a drug’s metabolic pathways
    Identify inhibition of cytochrome P450 (CYP) enzymes
  • Product Name
    Human Liver S9 Fraction-50 Donors (0.5 mL)
  • Product Type
    SubCellsular Fractions
  • Species
    Human
  • Source Organ
    Liver
  • Disease
    Normal
  • Product Type
    SubCellsular Fractions
  • Size/Quantity
    1 vial
  • Shipping Conditions
    Dry Ice
  • Storage
    -80°C

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