SKU: 1053APC

Human Liver Sinusoidal Endothelial Cells

Primary Cells > Liver & Biliary Cells

Product Type: Hepatic Cells

Species: Human

Cell Type: Endothelial Cells

Source Organ: Liver

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Cell Name: Human Liver Sinusoidal Endothelial Cells

  • Description
    Human Liver Sinusoidal Endothelial Cells (HLSECs) are isolated from human liver tissue. In vitro, these cells exhibit anchorage-dependent growth. They typically display an elongated or spindle-like morphology with fenestrations in their cytoplasm, which are characteristic of sinusoidal endothelial cells. HLSECs are highly specialized endothelial cells, and they play a crucial role in liver regeneration following acute liver injury. Through a cascade of complex physiological and molecular interactions, HLSECs initiate and support the repair and restoration of liver tissue structure and function. Moreover, HLSECs are involved in the pathogenesis of various liver-related diseases, such as the occurrence and development of hepatocellular carcinoma (HCC). The phenotypic plasticity of HLSECs during liver injury and repair positions them as important therapeutic targets for liver diseases.
  • Product Name
    Human Liver Sinusoidal Endothelial Cells
  • Product Type
    Hepatic Cells
  • Species
    Human
  • Cell Type
    Endothelial
  • Source Organ
    Liver
  • Disease
    Normal
  • Product Type
    Hepatic Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Liver Sinusoidal Endothelial Cells can be used to explore the pathogenesis of liver fibrosis, cirrhosis and liver cancer. These cells can also be used to study the liver immune microenvironment and evaluate the efficiency of drug clearance through the liver.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Liver Sinusoidal Endothelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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