SKU: 1074APC

Human Microglia Brain Immune Cells

Primary Cells > Brain & Nervous System Cells

Product Type: Nervous Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Brain

$1,249.00

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Cell Name: Human Microglia

Description

Human Microglia, a type of glial cell, are isolated from the human brain tissue. When cultured in vitro, these cells exhibit adherent growth. As the primary immune cells of the brain, they maintain a quiescent phenotype in the normal central nervous system (CNS), capable of expressing CD86 and CD40. Upon injury to the CNS, microglia transition to an active phenotype, releasing cytokines and reactive oxygen species. Human Microglia play a crucial role in neuronal development and neurodegenerative diseases. Beyond their immune surveillance function, human microglia play essential roles in synaptic pruning during neural development and contribute to the pathogenesis of various neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases.
Product Name

Human Microglia
Product Type

Nervous Cells
Species

Human
Cell Type

Microglia
Source Organ

Brain
Disease

Normal
Product Type

Nervous Cells
Growth Conditions

37 °C, 5% CO2
Application

Human Microglia can be used to test new therapies targeting neuroinflammation. It can be used to analyze the functions of risk genes such as TREM2 and CD33 in gene editing studies. It can also be co-cultured with neurons to simulate the neural-immune interaction mechanism.
Size/Quantity

1 vial
Recommended Medium And Supplement

Human Microglia Medium Kit
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Shipping Conditions

Dry Ice
Storage

Liquid Nitrogen
Biosafety Level

1

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