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SKU: 378BIC

Human OA Peripheral Blood Mononuclear Cells Osteoarthritis

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human OA Peripheral Blood Mononuclear Cells

  • Description
    Human OA Peripheral Blood Mononuclear Cells (hOA-PBMCs) are mainly isolated from the peripheral blood of patients with osteoarthritis (OA), including T cells, B cells, NK cells and monocytes. Peripheral blood from osteoarthritis (OA) patients.[1]. Morphologically, hOA-PBMCs are round or macrophage-like. PBMCs play an important role in immune regulation, inflammatory response and antigen presentation [2-3]. Round or macrophage-like morphology; mononuclear cells; mostly suspension growth typical of PBMCsIn the context of OA disease, PBMCs may participate in the chronic low-grade inflammatory process, exacerbating articular cartilage degradation and synovial inflammation by secreting proinflammatory cytokines (such as TNF-α, IL-1β, IL-6)Elevated expression of proinflammatory cytokines TNF-α, IL-1β, IL-6 in the OA context .Participate in chronic low-grade inflammation contributing to cartilage degradation and synovial inflammation in OA
  • Product Name
    Human OA Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Osteoarthritis
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human OA Peripheral Blood Mononuclear Cells can be used to study the immune mechanism of osteoarthritis, biomarker screening and drug efficacy evaluation, providing an important model for exploring the pathogenesis and therapeutic targets of OA.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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