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SKU: 1059APC

Human Oral Epithelial Cells

Primary Cells > Oral & Craniofacial Cells

Product Type: Oral Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Oral Cavity

$1,249.00
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Cell Name: Human Oral Epithelial Cells

  • Description
    Human oral epithelial cells are isolated from human oral mucosal tissue. These cells form the first line of defense for the oral mucosa, shielding it from microbial invasion and toxic agents.. In addition, they participate in immune responses by secreting inflammatory mediators (such as cytokines IL-1β, IL-6, IL-8) after infection, injury or immune stimulation [1-2]. Their ability to produce antimicrobial peptides (e.g., defensins and cathelicidins) further enhances the oral cavity’s defense mechanisms. HOECs also express epithelial-specific markers such as cytokeratins 13 and 14, E-cadherin, and involucrin, which are crucial for epithelial differentiation and barrier integrity. Abnormalities in HOEC function are closely associated with various oral diseases, including oral squamous cell carcinoma (where they undergo malignant transformation), recurrent aphthous ulcers (characterized by epithelial breakdown), and periodontal disease (involving epithelial barrier dysfunction).
  • Product Name
    Human Oral Epithelial Cells
  • Product Type
    Oral Cells
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Oral
  • Disease
    Normal
  • Product Type
    Oral Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Oral Epithelial Cells can be used as an in vitro cell model to study the pathogenesis of oral mucosal diseases, such as analyzing the effects of pathogenic factors on cell proliferation and apoptosis. They can also provide a toxicity testing and efficacy evaluation platform for drug development and verify the biocompatibility of candidate drugs with oral tissues.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Oral Epithelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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