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Human Ovarian Cancer Peripheral Blood Mononuclear Cells

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human Ovarian Cancer Peripheral Blood Mononuclear Cells

  • Description
    Human Ovarian Cancer Peripheral Blood Mononuclear Cells are immune cells isolated from the peripheral blood of ovarian cancer patients, primarily comprising lymphocytes (T cells, B cells, NK cells) and monocytes. These cells play a critical role in antitumor immune responses, including antigen presentation (monocytes/macrophages), cytotoxic activity (NK and CD8+ T cells), and antibody production (B cells). In ovarian cancer, PBMCs are often functionally impaired due to tumor-mediated immunosuppression, characterized by increased regulatory T cells (Tregs), myeloid-derived suppressor cells (MDSCs), and exhausted T cell phenotypes, which contribute to immune evasion and disease progression].
  • Product Name
    Human Ovarian Cancer Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Ovarian Cancer
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Ovarian Cancer Peripheral Blood Mononuclear Cells can be used to analyze the immune escape mechanism of ovarian cancer, such as detecting the increase in the proportion of regulatory T cells (Tregs) and the expansion of myeloid-derived suppressor cells (MDSCs). These cells can also be used to screen biomarkers that predict the efficacy of immune checkpoint inhibitors and evaluate the feasibility of adoptive cell therapies such as CAR-T.
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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