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SKU: 1189APC

Human Ovarian Surface Epithelial Cells

Primary Cells > Reproductive System Cells

Product Type: Female Reproductive Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Ovary

$1,249.00
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Cell Name: Human Ovarian Surface Epithelial Cells

  • Description
    Human Ovarian Surface Epithelial Cells (HOSECs) are primary cells isolated from the outer layer of healthy human ovaries. In vivo, these cells display diverse morphologies—squamous, cuboidal, and low columnar—and play a crucial role in ovulatory rupture and tissue repair. In culture, they form a cobblestone-like morphology and adhere strongly to surfaces. HOSECs express key markers like CK7, E-cadherin, and estrogen/progesterone receptors, verified by immunostaining. When co-cultured with endometrial stromal cells under estrogen-rich conditions, these cells form gland-like structures. These cells are early passage, non-tumorigenic, and widely utilized in research on ovarian cancer, epithelial-to-mesenchymal transition (EMT), and tissue regeneration. They offer insights into ovarian function and pathology, supporting both basic and translational studies.
  • Product Name
    Human Ovarian Surface Epithelial Cells
  • Product Type
    Female Reproductive Cells
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Ovarian
  • Disease
    Normal
  • Product Type
    Female Reproductive Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Ovarian Surface Epithelial Cells are widely used in research on the pathogenesis of epithelial ovarian cancer. Studies focused on the ovarian surface epithelium and its structural changes following ovulation, as well as their presence in ovarian carcinomas,play a crucial role in this research. Gaining insights into the abnormalities in cellular pathways is clinically significant as it helps in understanding OSE cell survival, apoptosis, transformation, and function during disease progression, ultimately help identify potential biomarkers for therapy and disease management.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Ovarian Surface Epithelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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