Free delivery over $100 Learn more

30 days return period Learn more
SKU: 1096APC

Human Pancreatic CAF-Stellate Cells

Primary Cells > Pancreatic & Islet Cells

Product Type: Human Primary Carcinoma Associated Fibroblasts

Species: Human

Cell Type: Fibroblasts

Source Organ: Pancreas

$1,249.00
Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: Human Pancreatic CAF-Stellate Cells

  • Description
    Human Pancreatic CAF-Stellate Cells are cancer-associated fibroblasts (CAFs) derived from pancreatic stellate cells (PSCs), playing a critical role in the tumor microenvironment (TME) of pancreatic cancer. Once activated, PSCs lose their lipid droplets and acquire a fibroblastic morphology, contributing to desmoplasia and ECM deposition. These cells are cultured as adherent monolayers with spindle-like morphology and exhibit moderate proliferative capacity. Typically used at low passage numbers (P3–P6) to preserve physiological relevance, they express key markers such as α-smooth muscle actin (α-SMA) and fibroblast activation protein (FAP), both indicative of their activated CAF phenotype. Functionally, they regulate immune evasion, fibrosis, and hypoxia in pancreatic tumors. Although they are non-tumorigenic, their presence enhances tumor progression. The cells are routinely tested and confirmed negative for mycoplasma and viral contaminants including HIV, HBV, HCV, and EBV.
  • Product Name
    Human Pancreatic CAF-Stellate Cells
  • Product Type
    Human Primary Carcinoma Associated Fibroblasts
  • Species
    Human
  • Cell Type
    Stellate Cell
  • Source Organ
    Pancreas
  • Product Type
    Human Primary Carcinoma Associated Fibroblasts
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Pancreatic CAF-Stellate Cells have important applications in understanding and targeting pancreatic cancer. CAFs are crucial in the progression and drug resistance of pancreatic cancer. Targeting these cancer-associated fibroblasts has emerged as a promising therapeutic strategy. Human Pancreatic CAFs can be implicated in various aspects of solid tumor biology, such as neoplastic progression, tumor growth, angiogenesis, and metastasis. Isolating and studying these cells provide insights into the heterogeneity of cancer-associated fibroblasts, leading to the development of more specific and personalized therapies for pancreatic cancer patients in the future.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Pancreatic Caf-Stellate Cells Medium Kit
  • Shipping Conditions
    Dry ice
  • Storage
    Liquid Nitrogen

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you