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SKU: 1070APC

Human Pancreatic Islets of Langerhans Cells

Primary Cells > Pancreatic & Islet Cells

Product Type: Pancreatic Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Pancreas

$1,249.00
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Cell Name: Human Pancreatic Islets of Langerhans Cells

  • Description
    Human Pancreatic Islets of Langerhans are derived from the human pancreas.These are primary, non-passaged cells typically used immediately after isolation or short-term culture. They do not proliferate significantly in vitro. They form dense clusters of cells within the pancreas, comprising different endocrine cell types. Pancreatic beta cells (or β cells), which function in insulin secretion, are the most abundant islet cell type, accounting for around 50–70% of human islet cells. There are also glucagon-secreting pancreatic alpha cells (or α cells), Delta cells (δ cells or D cells) secreting somatostatin, Epsilon cells (ε cells) secreting ghrelin, and pancreatic PP cells secreting polypeptides. Beta cells express insulin and transcription factors such as PDX1 and MAFA; alpha cells express glucagon and ARX; delta cells express somatostatin and HHEX. These markers can be detected via immunostaining or qPCR.These pancreatic cells collectively act to maintain glucose homeostasis and regulate other aspects of metabolism.
  • Product Name
    Human Pancreatic Islets of Langerhans Cells
  • Product Type
    Pancreatic Cells
  • Species
    Human
  • Cell Type
    Langerhans Cell
  • Source Organ
    Pancreatic Islet
  • Disease
    Normal
  • Product Type
    Pancreatic Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Pancreatic Islets of Langerhans Cells can be used as an in vitro cell model to study the pathogenesis of diabetes. These cells can also be used for the screening and development of hypoglycemic drugs.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Pancreatic Islets of Langerhans Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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