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SKU: 102BIC

Human Peripheral Blood Macrophages

Blood and Immune Cells & Products > Peripheral Blood Cells

Product Type: Blood Products

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human Peripheral Blood Macrophages

  • Description
    Human Peripheral Blood Macrophages are primary immune cells derived from peripheral blood monocytes of healthy adult donors.. The passage number is typically below 3 to maintain functional characteristics. In culture, these cells are adherent and exhibit an irregular, spread-out morphology. Macrophages play essential roles in both innate and adaptive immunity, responding to signals from damaged tissue and migrating to affected areas. They express key surface markers such as CD14, which serves as a co-receptor for bacterial lipopolysaccharide (LPS) detection, CD68, a lysosomal glycoprotein involved in phagocytosis, and HLA-DR, an MHC class II molecule crucial for antigen presentation. These markers are indicative of their activation state and functional capabilities. They are non-tumorigenic and do not exhibit uncontrolled proliferation.
  • Product Name
    Human Peripheral Blood Macrophages
  • Product Type
    Blood Products
  • Species
    Human
  • Cell Type
    Macrophage
  • Source Organ
    Peripheral Blood
  • Disease
    Normal
  • Product Type
    Blood Products
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Peripheral Blood Macrophages serve as a crucial research model due to the challenges associated with obtaining tissue macrophages in large quantities. They offer a valuable means to investigate various aspects of the immune system, macrophage-targeted therapies and polarization studies. Additionally, these macrophages are utilized to explore the immunopharmacological effects of compounds, such as their immunostimulatory, anti-inflammatory, and antioxidant effects.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Peripheral Blood Macrophages Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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