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SKU: 377BIC

Human Psoriasis Peripheral Blood Mononuclear Cells

Blood and Immune Cells & Products > Peripheral Blood Mononuclear Cells (PBMCs)

Product Type: Diseased Human Peripheral Blood Mononuclear Cells

Species: Human

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: Human Psoriasis Peripheral Blood Mononuclear Cells

  • Description
    Human Psoriasis Peripheral Blood Mononuclear Cells are isolated from the peripheral blood of patients with psoriasis, an immune-mediated chronic inflammatory skin disease. Peripheral blood from psoriasis patients.These cells are derived from the mononuclear cell fraction of the blood, which mainly includes lymphocytes (T cells, B cells, NK cells) and monocytes. Morphologically, PBMCs appear as small and round cells. They play a central role in the pathogenesis of psoriasis. Upregulated inflammatory cytokines IL-17 and TNF-α from activated T cellsAbnormal activation of T cells secretes inflammatory factors such as IL-17 and TNF-α, which in turn leads to excessive proliferation of keratinocytes and chronic inflammation. Central role in psoriasis pathogenesis by driving keratinocyte proliferation and maintaining chronic skin inflammation.
  • Product Name
    Human Psoriasis Peripheral Blood Mononuclear Cells
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Species
    Human
  • Cell Type
    Mononuclear Cell
  • Source Organ
    Peripheral Blood
  • Disease
    Psoriasis
  • Product Type
    Diseased Human Peripheral Blood Mononuclear Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Psoriasis Peripheral Blood Mononuclear Cells can be used to study the pathogenesis of psoriasis, providing insights into the systemic immune dysregulation underlying psoriasis and its associated complications, such as psoriatic arthritis and cardiovascular disease. In addition, these cells also provide a platform for evaluating treatment responses (e.g., biologics targeting the IL-17/23 pathway) and identifying potential biomarkers of disease progression
  • Size/Quantity
    1 vial
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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