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SKU: 1068APC

Human Pulmonary Alveolar Epithelial Cells

Primary Cells > Lung & Airway Cells

Product Type: Pulmonary Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Lung

$1,249.00
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Cell Name: Human Pulmonary Alveolar Epithelial Cells

  • Description
    Human Pulmonary alveolar epithelial cells (HPAEpiC), also called Human Pneumocytes, are isolated from human lung tissue. Human lung alveolar epithelial cells line the alveoli and comprise two subtypes of epithelial cells known as Type I Alveolar Cells (AT1) and Type II Alveolar Cells (AT2). These primary cells are typically used at early passages (P0–P3) due to their limited proliferative capacity in vitro.AT1 cells are large squamous cells that account for over 95% of the alveolar surface area,Type II cells are smaller than Type I and are scattered between AT1 cells near alveolar. Type I pneumocytes form the epithelial component of the thin air–blood barrier, while Type II pneumocytes secrete surfactants that form a fatty film to lowering surface tension. AT2 cells can also differentiate to replace damaged AT1 cells. Type II Alveolar cells contain Na+-, K+-ATPase and amiloride-sensitive epithelial Na+ channels
  • Product Name
    Human Pulmonary Alveolar Epithelial Cells
  • Product Type
    Pulmonary Cells
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Pulmonary Alveolar
  • Disease
    Normal
  • Product Type
    Pulmonary Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Pulmonary Alveolar Epithelial Cells can be used to explore the pathogenesis of diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and acute respiratory distress syndrome (ARDS), especially the molecular regulatory pathways of cell barrier function, inflammatory response, and oxidative stress. These cells can also be used to evaluate the efficacy and safety of inhaled drugs (such as glucocorticoids and antiviral drugs).
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Pulmonary Alveolar Epithelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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