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SKU: 1173APC

Human Rectal Smooth Muscle Cells

Primary Cells > Intestine & Gastrointestinal Cells

Product Type: Intestinal Cells

Species: Human

Cell Type: Smooth Muscle Cells

Source Organ: Intestine

$1,249.00
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Cell Name: Human Rectal Smooth Muscle Cells

  • Description
    Smooth muscle contraction is the fundamental event in gastrointestinal motion. Inflammation of the human intestine causes thickening of the smooth muscle layers which results from the increases in the smooth muscle-specific actins. The increased smooth muscle actins may affect force production and further demonstrate the plasticity of smooth muscle in the inflamed intestine. Human intestinal smooth muscle cells respond to IL-1-beta and TNF-alpha stimulation by releasing IL-6, which might significantly contribute to the overall systemic inflammatory response. Knowledge of molecular mechanism that underlies the control of colorectal smooth muscle tone is essential to advance of understanding of pathophysiology of the abnormality. The availability of human rectal smooth muscle cells in culture will considerably enhance our ability to study the contractile, proliferative and connective tissue responses of the smooth muscle of the human colorectal disorders.HRSMC Research Laboratories are isolated from the human rectum. HRSMC are cryopreserved at primary or passage one culture and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HRSMC are characterized by immunofluorescent method with antibodies to Α-smooth muscle actin and desmin. HRSMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HRSMC are guaranteed to further expand for 15 population doublings in the condition provided by our research lab.
  • Product Name
    Human Rectal Smooth Muscle Cells
  • Product Type
    Intestinal Cells
  • Species
    Human
  • Cell Type
    Smooth Muscle Cell
  • Source Organ
    Rectal
  • Disease
    Normal
  • Product Type
    Intestinal Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Rectal Smooth Muscle Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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