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SKU: 1111APC

Human Renal Cortical Epithelial Cells


Primary Cells > Kidney & Urinary Cells

Product Type: Renal Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Kidney


Regular price $1,249.00

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Cell Name: Human Renal Cortical Epithelial Cells

  • Description
    Renal epithelial cells (REpiC) play a crucial role in renal function. Similar to most other epithelial cells, renal epithelial cells display a polarized morphology which is essential for their function. They reabsorb nearly all of the glucose and amino acids in the glomerular filtrate, while allowing other substances of no nutritional value to be excreted in the urine. Human REpiC are capable of internalizing bacteria. They are also a major site of injury in a variety of congenital, metabolic, and inflammatory diseases. REpiC can produce inflammatory mediators such as cytokines and chemokines and actively participate in acute inflammatory processes by affecting and directing leukocyte chemotaxis via the production of IL-8. REpiC express IL-2R alpha and MHC class II antigens during inflammation, indicating their capacity to participate in the pathogenesis of immune renal injury. To be able to study the relationship between renal epithelial cells and a variety of renal diseases, the HREpiC culture provides a useful in vitro model.HRCEpiC Research Laboratories are isolated from human kidneys. HRCEpiC are cryopreserved at passage one and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HRCEpiC are characterized by immunofluorescent method with antibodies to cytokeratin-18, -19 and vimentin. HRCEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HRCEpiC are guaranteed to further expand for 15 population doublings in the condition provided by our research lab.
  • Product Name
    Human Renal Cortical Epithelial Cells
  • Product Type
    Renal Cells
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Kidney
  • Disease
    Normal
  • Product Type
    Renal Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Renal Cortical Epithelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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