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SKU: 0960APC

Human Retinal Muller Cells

Primary Cells > Eye Cells

Product Type: Ocular Cells

Species: Human

Cell Type: Glial Cells

Source Organ: Eye

$1,249.00
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Cell Name: Human Retinal Muller Cells

  • Description
    Human Retinal Muller Cells are derived from the human retina. Following the primary culture, these cells are cryopreserved. Muller cells are the principal glial cells of the retina, extending across its entire thickness and providing structural and metabolic support to retinal neurons. They maintain homeostasis, regulate extracellular ion balance, remove neurotransmitters, and contribute to the blood-retinal barrier. Studies have shown that Muller cells are implicated in various retinal diseases, including diabetic retinopathy, retinal detachment, and age-related macular degeneration. Repeated freezing and thawing should be avoided during the culture process.
  • Product Name
    Human Retinal Muller Cells
  • Product Type
    Ocular Cells
  • Species
    Human
  • Cell Type
    Muller Cell
  • Source Organ
    Retina
  • Disease
    Normal
  • Product Type
    Ocular Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Retinal Müller Cells are tools for studying the human retina and understanding retinal diseases. Müller cells play a critical role in retinal health, and their vulnerability is closely linked to photoreceptor cell pathology, particularly during aging. These cells are useful for research into the various, yet not fully understood, roles they play in retinal diseases. Investigating Müller cell functions and dysfunctions can provide insights into retinal disease mechanisms. Additionally, their ability to dedifferentiate into progenitor-like cells holds promise for future therapeutic approaches. A deeper understanding of the gliotic mechanisms underlying reactive Müller cells can aid in developing strategies that enhance their protective and regenerative properties while reducing their toxicity, potentially leading to more effective treatments for retinal disorders.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Retinal Muller Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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