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SKU: 014SRC

Human Schwann Cells


Specialized Research Cells > Brain & Nervous System Cells

Product Type: Nervous Cells

Species: Human

Cell Type: Glial Cells

Source Organ: Nervous System


Regular price $1,249.00

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Cell Name: Human Schwann Cells

  • Description
    Human Schwann Cells are derived from the peripheral nervous system. They are a type of glial cells and play an important role in supporting the development, function, and regeneration of peripheral nerves. These cells are able to secrete various growth factors to promote axonal growth, such as nerve growth factor, brain-derived neurotrophic factor, ciliary neurotrophic factor, neurotrophin-3, fibroblast growth factor and conserved dopamine neurotrophic factor. Schwann cells exhibit bipolar or tripolar morphology and grow in an adherent monolayer in vitro.Following nerve injury, Schwann cells undergo phenotypic changes to create a regenerative microenvironment by clearing myelin debris, forming regeneration tracks (Büngner bands), and upregulating growth factor production.They express characteristic markers such as S100β, p75^NTR, GFAP, and myelin protein zero (MPZ). Their plasticity and regenerative capacity make them promising candidates for cell-based therapies in peripheral nerve repair and neurodegenerative diseases.
  • Product Name
    Human Schwann Cells
  • Product Type
    Nervous Cells
  • Species
    Human
  • Cell Type
    Schwann Cell
  • Source Organ
    Peripheral Nerves
  • Disease
    Normal
  • Product Type
    Nervous Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Schwann Cells obtained via in vitro culture are found useful for correcting the deficiencies of an injury or disease. Human Schwann Cell model system has great potential in therapeutic genes and drugs screening, treatment for acquired and inherited demyelinating neuropathies. These cells from specific patient could be used to study an onset to understand mechanisms.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Schwann Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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