SKU: 1152APC

Human Splenic Endothelial Cells

Primary Cells > Lymphoid & Immune Tissue Cells

Product Type: Spleen Cells

Species: Human

Cell Type: Endothelial Cells

Source Organ: Spleen

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Cell Name: Human Splenic Endothelial Cells

  • Description
    Human Splenic Endothelial Cells are derived from human spleen tissue. These cells are endothelial-like and grow in an adherent manner. These are primary cells typically used at low passage to preserve phenotypic characteristics.The cells have a variety of important functions, including forming the structural basis of microvessels, participating in regulating vascular permeability and integrity, and playing a key role in immune response and inflammatory response by releasing cytokines and other bioactive substances. They express endothelial markers such as CD31 (PECAM-1), von Willebrand factor (vWF), and VE-cadherin, typically identified by immunocytochemistry or flow cytometry.Karyotype is generally normal in early passages and not routinely assessed.They are important for maintaining the normal function of the spleen and preventing infection, while providing a supportive microenvironment for the development of dendritic cells.
  • Product Name
    Human Splenic Endothelial Cells
  • Product Type
    Spleen Cells
  • Species
    Human
  • Cell Type
    Endothelial
  • Source Organ
    Spleen
  • Disease
    Normal
  • Product Type
    Spleen Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Splenic Endothelial Cells can be used to explore the immune regulation mechanisms of the spleen, such as how they participate in antigen presentation, lymphocyte migration, and inflammatory responses. These cells can also be used to evaluate drug metabolism, the targeted delivery of nanoparticles, or the mechanism of action of immunomodulatory drugs.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Splenic Endothelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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