Free delivery over $100 Learn more

30 days return period Learn more
SKU: 1151APC

Human Splenic Fibroblasts Spleen

Primary Cells > Lymphoid & Immune Tissue Cells

Product Type: Spleen Cells

Species: Human

Cell Type: Fibroblasts

Source Organ: Spleen

$1,249.00
Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: Human Splenic Fibroblasts

  • Description
    Human Splenic Fibroblasts are primary cells isolated from the spleen of healthy human donors, a key secondary lymphoid organ essential for immune regulation and hematopoiesis. Derived specifically from the white pulp, they exhibit spindle-shaped fibroblast-like morphology and adherent growth in vitro. These fibroblasts include T-zone reticular cells (CCL21⁺), follicular dendritic cells (CXCL13⁺, CR1/2⁺), and marginal reticular cells (CXCL13⁺, MAdCAM1⁺, RANKL⁺). Functionally, they regulate lymphocyte migration, antigen presentation, and splenic architecture. Their immunomodulatory nature and in vitro adaptability make them valuable in immunology, vascular biology, and stromal research. They express PDGFRβ, CD90, and vimentin, confirmed by flow cytometry and immunocytochemistry. These non-immortalized cells cannot be passaged indefinitely, preserving native function. All samples are negative for HIV-1, HIV-2, HBV, HCV, and mycoplasma to ensure biosafety.
  • Product Name
    Human Splenic Fibroblasts
  • Product Type
    Spleen Cells
  • Species
    Human
  • Cell Type
    Fibroblast
  • Source Organ
    Spleen
  • Disease
    Normal
  • Product Type
    Spleen Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human splenic fibroblasts can be used to identify receptors and markersinvolved in proliferation, tissue repair, and inflammation. They are useful for establishing in vitro disease models for high-throughput and high-content screening, allowing researchers to investigate disease mechanisms and test potential interventions. Additionally, studying the role of spleen fibroblasts in the spleen’s structure and their modulation of surrounding immune cells provides insights into immune functions and host defense mechanisms.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Splenic Fibroblasts Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you