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SKU: 1069APC

Human Type II Alveolar Epithelial Cells

Primary Cells > Lung & Airway Cells

Product Type: Pulmonary Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Lung

$1,249.00
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Cell Name: Human Type II Alveolar Epithelial Cells

  • Description
    Human Type II Alveolar Epithelial Cells are isolated from human lung tissue, playing a critical role in maintaining the alveoli integrity and function. Morphologically, these cells exhibit a cuboidal shape with apical microvilli and cytoplasmic lamellar bodies. In vitro, the cells show adherent growth. Type II Alveolar Epithelial Cells secrete cytokines such as IL-6 as well as chemokines like CXCL8. They play key roles in pulmonary surfactant production, alveolar repair, immune modulation, and fluid homeostasis. They characteristically express surfactant proteins, especially surfactant protein C (SP-C), which is essential for alveolar stability and serves as a specific marker for type II alveolar cells. Their ability to proliferate and differentiate makes them crucial for lung regeneration after injury, while dysfunction contributes to respiratory diseases such as pulmonary fibrosis, acute respiratory distress syndrome (ARDS), and COVID-19-related lung damage.
  • Product Name
    Human Type II Alveolar Epithelial Cells
  • Product Type
    Pulmonary Cells
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Lung
  • Disease
    Normal
  • Product Type
    Pulmonary Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Type II Alveolar Epithelial Cells can be used for mechanism exploration, drug screening and toxicity assessment of lung diseases such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD). They can also be used to evaluate the cytotoxicity and metabolic characteristics of inhaled drugs (such as glucocorticoids or antiviral drugs).
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Type II Alveolar Epithelial Cells Medium Kit
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen

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