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SKU: 1132APC

Human Urothelial Cells

Primary Cells > Kidney & Urinary Cells

Product Type: Urethral Cells

Species: Human

Cell Type: Epithelial Cells

Source Organ: Bladder

$1,249.00
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Cell Name: Human Urothelial Cells

  • Description
    Human urothelial cells are primary epithelial cells isolated from normal bladder tissue of human donors. These cells exhibit epithelial-like morphology with adhere to culture surfaces, forming a stratified barrier that lines the urinary tract. Typically cryopreserved after initial culture, they retain limited proliferative capacity. Functionally, urothelial cells maintain urinary barrier integrity through uroplakin-rich apical membranes enriched with uroplakins and the formation of tight junctions. Key differentiation markers include cytokeratin 20 (CK20), expressed in mature umbrella cells and uroplakins (UPK1/2) . These cells are intrinsically linked to urothelial carcinoma pathogenesis of urothelial carcinoma and chronic inflammatory condistion such as interstitial cystitis.
  • Product Name
    Human Urothelial Cells
  • Product Type
    Urethral Cells
  • Species
    Human
  • Cell Type
    Urothelial Cell
  • Source Organ
    Urothelial
  • Disease
    Normal
  • Product Type
    Urethral Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human urothelial cells serve as a valuable in vitro model for various research applications. Their cultivation enables the study of immunoregulatory functions of urothelium and supports the development of disease models relevant to urinary tract. Moreover, they are particularly useful for high-throughput and high-content screening. Additionally, these cells provide a robust systme for investigating epithelial proliferation, stratification, and differentiation processes, making them indispensable tools in regenerative medicine, toxicology, and cancer research.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Urothelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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