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SKU: 1240APC

Human Uterine Fibroblasts Uterus

Primary Cells > Reproductive System Cells

Product Type: Female Reproductive Cells

Species: Human

Cell Type: Fibroblasts

Source Organ: Uterus

$1,249.00
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Cell Name: Human Uterine Fibroblasts

  • Description
    Human Uterine Fibroblasts (HUF) are primary cells isolated from human uterine wall tissue. These cells exhibit a typical spindle-shaped or star-like morphology with large, pale nuclei and transparent cytoplasm. They show high levels of vimentin, CD90 and fibroblast activation protein (FAP) expression. Functionally, HUF play important roles in extracellular matrix remodeling, particularly during uterine repair and inflammatory responses, and are implicated in pathological processes such as uterine fibroids due to their dysregulated collagen secretion and fibrotic activity.
  • Product Name
    Human Uterine Fibroblasts
  • Product Type
    Female Reproductive Cells
  • Species
    Human
  • Cell Type
    Fibroblast
  • Source Organ
    Uterus
  • Disease
    Normal
  • Product Type
    Female Reproductive Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Human Uterine Fibroblasts (HUF) serve as a powerful tool for investigating uterine physiology and pathology. These cells are widely utilized to study extracellular matrix (ECM) remodeling mechanisms in conditions like uterine fibroids and endometriosis, where dysregulated collagen deposition drives fibrotic progression. Researchers use HUF to model hormonal interactions, particularly responses to estrogen and progesterone, which influence uterine tissue repair and inflammatory signaling. Their role in cell-cell communication also makes them valuable for co-culture systems with uterine smooth muscle or immune cells to mimic disease microenvironments.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Human Uterine Fibroblast Medium Kit
  • Quality Control
    All cells test negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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