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SKU: 0249ATC

HuP-T3 Human Pancreas Epithelial Cells

Tumor Cell Lines > Pancreatic Cancer Cell Lines

Product Type: Human Pancreas Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Pancreas

$1,249.00
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Cell Name: HuP-T3

Tissue: pancreas; Tumor: adenocarcinoma; Derived from ascitic fluid. CEA production.

  • Description
    HuP-T3 is a human pancreatic adenocarcinoma cell line derived from the ascites fluid of a 66-year-old Japanese male patient. This epithelial-like cell line exhibits adherent growth properties and demonstrates a doubling time of approximately 40–50 hours. Genomic profiling reveals critical mutations in KRAS (p.Gly12Arg), TP53 (p.Arg282Trp), and MSH6 (p.Lys1358fs*2. When xenografted into nude mice, HuP-T3 form poorly differentiated adenocarcinomas, confirming their tumorigenic potential. These characteristics position HuP-T3 as a valuable and physiologically relevant tool for investigating pancreatic cancer pathogenesis and therapeutic response mechanisms.
  • Product Name
    HuP-T3
  • Product Type
    Human Pancreas Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Pancreas
  • Product Type
    Human Pancreas Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The HuP-T3 cell line serves as a valuable model for pancreatic cancer research, particularly in studies focused on tumor invasion, migration, and metastasis.. It offers an effective platform to explore the molecular signaling pathways such as those involving KRAS and p53, which drive the aggressive behavior of pancreatic tumors. HuP-T3 cells are widely used in preclinical drug screening, enabling researchers to evaluate the efficacy of novel anticancer compounds and targeted therapies. Furthermore, its defined genetic alterations make it ideal for studying the cellular response to genotoxic stress, supporting the development of precision oncology strategies.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    EMEM + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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