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SKU: 0690ATC

IST MES2 Human Pleural Epithelioid Mesothelioma Specialized Cells

Tumor Cell Lines > Melanoma Cell Lines

Product Type: Human Melanoma Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Other

$1,249.00
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Cell Name: IST MES2

Species: human, Caucasian male 71 years old; Tissue: pleural effusion; Tumor: mesothelioma.

  • Description
    IST MES2 is an epithelial-like cell that was originally isolated from the pleural effusion of a 71-year-old, Caucasian male patient with malignant pleural mesothelioma (MPM). IST MES2 exhibits epithelial-like morphology and adherent culture properties. IST MES2 cell are able to express stemness markers such as CD24, ABCG2 and OCT4 that it can be utilised in the research for mechanisms of MPM drug resistance and metastasis. In certain culture condition, IST MES2 cell can growth as a non-adherent spherical clusters to study the tumor infiltration cells in mesothelioma.
  • Product Name
    IST MES2
  • Product Type
    Human Melanoma Cell Lines
  • Species
    Human
  • Disease
    Pleural Epithelioid Mesothelioma
  • Product Type
    Human Melanoma Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The IST MES2 cell line holds significant s in various aspects of malignant pleural mesothelioma (MPM) research. It serves as an essential tool to highlight the biology of MPM and evaluate the efficacy of new antiproliferative compounds. Additionally, IST MES2 is a valuable cell model for identifying novel targets for innovative pharmacological therapy against MPM. Moreover, it aids in proposing molecular pathways for potential pharmacological targets, paving the way for personalized medicine in MPM patients. Furthermore, the cell line allows investigation into the development of resistance to receptor-induced cell death in malignant mesothelial cells, providing insights into therapeutic challenges and potential solutions for MPM treatment.
  • Size/Quantity
    1 vial
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    2

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