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SKU: 0525ATC

KARPAS 299 Human Lymphoma Lymphoma Lymphoblastoid Cells


Tumor Cell Lines > Lymphoma Cell Lines

Product Type: Human Lymphoma Cell Lines

Species: Human

Cell Type: Lymphoblastoid Cells

Source Organ: Lymphatic System


Regular price $1,249.00

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Cell Name: KARPAS 299

A human T cell lymphoma cell line established from the peripheral blood of a 25-year-old man with T cell non-Hodgkin′s lymphoma in 1986.

  • Product Name
    KARPAS 299
  • Product Type
    Human Lymphoma Cell Lines
  • Species
    Human
  • Cell Type
    Lymphoblastoid
  • Source Organ
    Lymphoma
  • Disease
    Anaplastic Large Cell Lymphoma
  • Product Type
    Human Lymphoma Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    KARPAS 299 is a critical tool in lymphoma research, widely used to explore the molecular mechanisms of the t(2;5) translocation and the oncogenic activity of the NPM-ALK fusion protein. It is particularly valuable for characterizing CD30-positive large cell lymphomas and dissecting the signaling pathways involved in ALCL pathogenesis. This cell line supports the development and testing of targeted therapies, especially those aimed at ALK and CD30, such as monoclonal antibodies and small-molecule inhibitors. Its utility in xenograft models further enhances its relevance in translational research and therapeutic discovery for aggressive T-cell lymphomas.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 2mM Glutamine + 20% FBS
  • Shipping Conditions
    Dry ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    2

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