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SKU: 130NTC

L929 Mouse Adipose Fibroblasts Cell Line


Non-Tumor Continuous Cell Lines > Fibroblast Cell Lines

Product Type: Mouse Fibroblas Lymphocytes Cell Lines

Species: Mouse

Cell Type: Fibroblasts

Source Organ: Adipose


Regular price $1,249.00

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Cell Name: L929

Mouse C3H/An connective tissue. Subclone of parental strain L, established by W R Earle in 1940. One of the first to be established in continuous culture. The L strain was derived from normal subcutaneous areolar and adipose tissue of a 100 day old male.

  • Description
    L929 cells are fibroblast-like, adherent cells derived from the subcutaneous tissue of a 100-day-old male C3H/An mouse. They are commonly used in cytotoxicity and biocompatibility assays, especially in biomaterials and tissue engineering. Due to their sensitivity to TNF, they are valuable for cytokine and inflammation studies. Additionally, their susceptibility to viruses like IBDV makes them useful in virology research, including viral replication and antiviral testing. Cells are APRT+ and HPRT+.
  • Product Name
    L929
  • Product Type
    Mouse Fibroblas Lymphocytes Cell Lines
  • Species
    Mouse
  • Cell Type
    Fibroblast
  • Source Organ
    Adipose
  • Disease
    Normal
  • Product Type
    Mouse Fibroblas Lymphocytes Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    L929 cells are widely used in biological science due to their versatility and functional relevance. They serve as a standard model for in vitro cytotoxicity assay, aiding in the evaluation of potential adverse effects of various compounds. Additionally, L929 cells serves as an alternative source of macrophage colony-stimulating factors (M-CSF), facilitating research in immunology and cell biology. Moreover, the protein composition found in the L929 supernatant offers valuable insights into the activation state during the differentiation of bone marrow-derived macrophages (BMDMs) Their robust response to stimuli also makes them valuble for research in immunology, inflammation, and drug screening.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    EMEM + 10% HS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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