SKU: 0609ATC

LS-180 Human Colon Colorectal Adenocarcinoma Epithelial Cells

Tumor Cell Lines > Colon Cancer Cell Lines

Product Type: Human Colon Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Intestine

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Cell Name: LS-180

Human Caucasian colon adenocarcinoma. Derived from a 58 year old female Caucasian with Dukes type B adenocarcinoma of the colon. The cells secrete CEA and mucin and are tumorigenic in nude mice. LS174T was derived from the same patient.

  • Description
    LS-180 is a human epithelial colorectal adenocarcinoma cell line that was originally isolated and established from the large intestine and colon tissue of a 58-year-old white female patient with colon adenocarcinoma (Dukes type B adenocarcinoma). JHH-7 is a goblet cell that exhibits epithelial-like morphology and adherent culture properties. The stemline karyotype of LS-180 cells is 45, t(X;5) (q12;q31) are likely occurring translocation; 2.2% of cells were tetraploid. LS-180 can express a higher level of CEA than other human colorectal adenocarcinoma cell strains, making it an ideal candidate for gastrointestinal tract research.
  • Product Name
    LS-180
  • Product Type
    Human Colon Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Colon
  • Disease
    Colorectal Adenocarcinoma
  • Product Type
    Human Colon Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    LS-180 cell line serves as a valuable resource in the investigation of intestinal transporter regulation. Additionally, it constitutes a strong model for conducting mechanistic studies on AHR-regulated CYP1A2 expression. Moreover, LS-180 is recognized as an exceptional tool for studying the pregnane X receptor. Its multiple s make LS-180 a crucial asset in advancing research in these specific areas of interest.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    EMEM + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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