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SKU: 0586ATC

MCA-RH 7777 Rat Liver Hepatoma Hepatocytes Cell Line

Tumor Cell Lines > Liver Cancer Cell Lines

Product Type: Rat Liver Cancer Cell Lines

Species: Rattus Norvegicus

Cell Type: Hepatocytes

Source Organ: Liver

$1,249.00
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Cell Name: MCA-RH 7777

Rat Buffalo hepatoma. Derived from the Morris hepatoma 7777 (obtained from a male Buffalo strain rat). The original tumour was induced with N-2 fluorenylphthalamic acid. Particularly interesting for oncogeny studies since the cells produce alpha-fetoprot.

  • Description
    MCA-RH 7777 is an animal cell line that was originally isolated from the liver tissue of a female rat with hepatocellular carcinoma. MCA-RH 7777 exhibits epithelial-like morphology with a distinctive fusiform and polygonal appearance and loosely adherent culture properties. In vitro, the McA-RH 7777 cells express glucocorticoid and α-fetoprotein (AFP). The glucocorticoid treatment may increase the cell proliferation and inhibit alpha-fetoprotein production. MCA-RH 7777 expresses both H3-receptor (H3R) transcripts and proteins; its proliferation is modulated by HA via interactions with autoinhibitory H3Rs.
  • Product Name
    MCA-RH 7777
  • Product Type
    Rat Liver Cancer Cell Lines
  • Species
    Rattus Norvegicus
  • Cell Type
    Hepatocyte
  • Source Organ
    Liver
  • Disease
    Hepatoma
  • Product Type
    Rat Liver Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The versatile MCA-RH 7777 cell line serves a multitude of purposes in scientific exploration. It plays a pivotal role in researching liver cancer metastasis, recurrence patterns, and innovative interventional therapies, while also contributing significantly to drug screening initiatives. Beyond this, the cell line is instrumental in tumorigenicity and oncogeny studies, shedding light on crucial aspects of cancer development. Additionally, it offers a valuable platform for investigating the intricate mechanisms governing the biogenesis of plasma lipoproteins.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    EMEM + 20% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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