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SKU: 0263ATC

MIA PaCa-2 Human Adenocarcinoma Specialized Cells

Tumor Cell Lines > Pancreatic Cancer Cell Lines

Product Type: Human Pancreas Cancer Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Other

$1,249.00
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Cell Name: MIA PaCa-2

Human cell line derived from pancreatic cancer

  • Description
    MIA PaCa-2 is a human pancreatic tumor cell line originally derived from the pancreas of a 65-year-old Caucasian male patient with pancreatic ductal adenocarcinoma (PDAC). The cells exhibit epithelial-like morphology and semi-adherent growth characteristics, typically forming loosely attached clusters. The karyotype of MIA PaCa-2 shows hypotriploid, with a 61 of model chromosome number (PMID: 832918). MIA PaCa-2 contain abundant cytoplasm and are known to be sensitive to L-asparaginase treatment. As a tumorigenic cell line, MIA PaCa-2 readily forms tumors when subcutaneously implanted into immunodeficient (nude) mice, making it suitable for in vivo cancer studies.
  • Product Name
    MIA PaCa-2
  • Product Type
    Human Pancreas Cancer Cell Lines
  • Species
    Human
  • Disease
    Pancreatic Ductal Adenocarcinoma
  • Product Type
    Human Pancreas Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    MIA PaCa-2, is a widely used model for pancreatic cancer research, serves as a crucial tool in elucidating the biology of pancreatic ductal adenocarcinoma,particularly in studies of tumor progression, metastatic potential, and resistance to chemoradiotherapy. Additionally, MIA PaCa-2 is frequently used to analyze the morphological features of PDAC cells and to understand the cellular and molecular changes involved in pancreatic cancer development. This valuable information not only enhances our understanding of pancreatic ductal adenocarcinoma (PDAC) but also paves the way for the discovery of novel diagnostic biomarkers development of targeted therapies, contributing to more personalized and effective treatment strategies for pancreatic cancer patients.
  • Size/Quantity
    1 vial
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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