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SKU: 0492APC

Mouse Colonic Fibroblasts

Primary Cells > Intestine & Gastrointestinal Cells

Product Type: Colonic Cells

Species: Mouse

Cell Type: Fibroblasts

Source Organ: Intestine

$1,249.00
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Cell Name: Mouse Colonic Fibroblasts

  • Description
    Mouse Colonic Fibroblasts (MCFs) are primary cells isolated from the colon tissue of adult mice, typically C57BL/6 strain. These cells exhibit a spindle-shaped morphology and express α-smooth muscle actin (α-SMA), characteristic of myofibroblasts. MCFs play a crucial role in extracellular matrix (ECM) production and remodeling, contributing to tissue homeostasis and repair. They are involved in the pathogenesis of various gastrointestinal disorders, including inflammatory bowel disease (IBD) and colorectal cancer. MCFs can be cultured and expanded in vitro for several passages, maintaining their proliferative capacity and functional properties. They serve as valuable models for studying fibroblast biology, fibrosis, and the molecular mechanisms underlying intestinal diseases.
  • Product Name
    Mouse Colonic Fibroblasts
  • Product Type
    Colonic Cells
  • Species
    Mouse
  • Cell Type
    Fibroblast
  • Source Organ
    Colon
  • Disease
    Normal
  • Product Type
    Colonic Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Mouse Colonic Fibroblasts (MCFs) are utilized to investigate ECM remodeling and fibrosis in gastrointestinal research. They are employed in studies examining the role of fibroblasts in inflammation and tissue repair processes. MCFs serve as models to explore the molecular mechanisms underlying gastrointestinal disorders, including IBD and colorectal cancer. Additionally, they are used to assess the effects of various stimuli on fibroblast activation and function, providing insights into therapeutic strategies for managing fibrotic diseases.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Mouse Colonic Fibroblasts Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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