SKU: 0618APC

Mouse Hippocampal Astrocytes Brain

Primary Cells > Brain & Nervous System Cells

Product Type: Mouse Primary Cells

Species: Mouse

Cell Type: Glial Cells

Source Organ: Brain

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Cell Name: Mouse Hippocampal Astrocytes

  • Description
    Mouse Hippocampal Astrocytes are primary cells isolated from the hippocampus of neonatal mice. These astrocytes, critical for neural functioning, form a tightly coupled network in the hippocampus, a key region for spatial memory. Disruption of this network can affect neuronal excitability and synaptic transmission. Inhibition of vesicle release impairs recognition memory, while chemogenetic activation enhances contextual fear memory, demonstrating their role in memory. Morphologically, they exhibit astrocytic characteristics and are GFAP – positive. They are tested free of HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. Ideal for investigating molecular mechanisms of astrocytic physiology and their influence on cognition, these cells provide a reliable platform for brain development studies.
  • Product Name
    Mouse Hippocampal Astrocytes
  • Product Type
    Mouse Primary Cells
  • Species
    Mouse
  • Cell Type
    Astrocyte
  • Source Organ
    Brain
  • Disease
    Normal
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Investigating mouse hippocampal astrocytes provide critical insights into their region-specific roles, molecular regulation, and physiological characteristics. By studying these cells, researchers can unravel the molecular controls that shape astrocytic fate and physiology, as well as understand how evolutionary changes in astrocytes influence advanced cognitive processes. Furthermore, exploring the role of astrocytes in neural signaling and cognitive integration enhances our understanding of brain function. Although much of our knowledge about astrocytes comes from in vitro studies, the continued use of astrocyte cultures in experimental research enables the exploration of the diverse properties of astrocytes and their contributions to brain function.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Mouse Astrocytes Hippocampal Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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