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SKU: 0605APC

Mouse Lymphatic Endothelial Cells

Primary Cells > Lymphoid & Immune Tissue Cells

Product Type: Mouse Primary Cells

Species: Mouse

Cell Type: Endothelial Cells

Source Organ: Lymphatic System

$1,249.00
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Cell Name: Mouse Lymphatic Endothelial Cells

  • Description
    Mouse Lymphatic Endothelial Cells (MLECs) are primary cells isolated from healthy murine lymphatic tissues. These cells exhibit a cobblestone-like or oak-leaf morphology and display adherent growth properties. These cells retain key physiological functions including maintaining fluid and protein homeostasis, regulating immune responses, and facilitating lymphocyte recirculation. They are involved in various pathological processes like lymphedema, lymphangitis, and tumor metastasis, largely due to their role in lymphatic remodeling and immune modulation. MLECs express lymphatic-specific markers, including CD31 and LYVE-1. As primary cells, MLECs have limited proliferative capacity (typically ≤5 passages) and require optimized culture conditions to preserve functionality.
  • Product Name
    Mouse Lymphatic Endothelial Cells
  • Product Type
    Mouse Primary Cells
  • Species
    Mouse
  • Cell Type
    Endothelial
  • Source Organ
    Lymphatic
  • Disease
    Normal
  • Product Type
    Mouse Primary Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    MLECs are widely employed in studies of lymphatic vessel biology under both physiological and pathological conditions. These cells serve as a critical in vitro model for investigating lymphangiogenesis, immune cell trafficking, and molecular transport mechanisms, particularly in cancer metastasis and chronic inflammatory disorders like lymphedema. Researchers employ MLECs to model tumor-induced lymphatic remodeling, to screen anti-metastatic drugs targeting VEGF-C/VEGFR-3 signaling, and to assess endothelial permeability in infection or autoimmune settings.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Mouse Lymphatic Endothelial Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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