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Mouse Splenocytes Spleen Immune Cells

Blood and Immune Cells & Products > Lymphocytes & Splenocytes

Product Type: Mouse Primary Cells

Species: Mouse

Cell Type: Immune Cells

Source Organ: Spleen

$1,249.00
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Cell Name: Mouse Splenocytes

  • Description
    Mouse Splenocytes are primary immune cells isolated from the spleen tissue of mice (Mus musculus), They constitute a heterogeneous population of lymphocytes, including T-cells, B-cells, Natural Killer (NK) cells, and NKT-cell. These cells are derived from normal, disease-free donors and are cryopreserved after isolation to maintain high viability and functionality. Morphologically, splenocytes are mononuclear and maintained in suspension culture. They play an important role in adaptive immunity, including antigen presentation, antibody production, and cytokine secretion. They are widely utilized in research on autoimmune diseases, such as type 1 diabetes and multiple sclerosis. These cells express characteristic surface markers like CD3 (T-cells), CD19/CD45R (B-cells), CD4 (helper T-cells), and CD8 (cytotoxic T-cells). Due to their sensitivity to freeze-thaw cycles, repeated cryopreservation should be avoided to preserve cell integrity.
  • Product Name
    Mouse Splenocytes
  • Product Type
    Mouse Primary Cells
  • Species
    Mouse
  • Cell Type
    Splenocyte
  • Source Organ
    Spleen
  • Disease
    Normal
  • Product Type
    Mouse Primary Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Mouse splenocytes play a pivotal role in a wide array of immunological research applications. They are commonly employed in various in-vitro immunoassays, including but not limited to ELISPOT, mixed lymphocyte reactions, and cytotoxicity assays measuring antibody-dependent cellular cytotoxicity (ADCC) or complement-dependent cytotoxicity (CDC). Moreover, their significance extends to ex-vivo applications for comprehensive immune cell population profiling and genetic modification via retroviral transduction. These capabilities highlight their indispensable role in advancing immunological research and therapeutic discovery.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Mouse Splenocytes Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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