SKU: 0550ATC

MT-2 Human Lymphocyte Lymphoblasts Cell Line

Tumor Cell Lines > Leukemia Cell Lines

Product Type: Human Leukemia Cell Lines

Species: Human

Cell Type: Lymphoblasts

Source Organ: Lymphatic System

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Cell Name: MT-2

Human T cell leukaemia. Derived from a 45 year old Japanese female with generalised lymphadenopathy and heptosplenomegaly (Adult T-cell Leukaemia) by co-culture of her peripheral leukocytes with male umbilical cord lymphocytes.

  • Description
    MT-2 is a human cord T cell line that was originally established by co-cultivation of the peripheral leukocytes from a 45-year-old female T-cell leukemia patient with cord leukocytes from a male infant. MT-2 exhibits lymphoblast-like morphology and semi-adherent culture properties. The stemline karyotype of MT-2 is diploid with a male chromosomal pattern. This cell line displays typical T-cell characteristics, including expression of sheep red blood cells and complement receptors. MT-2 cells are persistently infected with type-C virus particles (ATLV) and are positive for ATL-associated antigens (ATLA), which are specifically recognized by sera from ATL patients.
  • Product Name
    MT-2
  • Product Type
    Human Leukemia Cell Lines
  • Species
    Human
  • Cell Type
    Lymphoblast
  • Source Organ
    Lymphocyte
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The MT-2 cell line exhibits phenotypic and functional characteristics similar to regulatory T cells (Tregs), making it a valuable model for studying Treg biology. These cells harbor HTLV-1 and support HIV replication, providing a platform for investigating virus-host interactions. MT-2 cells are also essential for exploring viral tropism, which is important in clinical decision-making and treatment development for infectious diseases.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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