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SKU: 0160ATC

NB-4 Human Leukemia Specialized Cells

Tumor Cell Lines > Leukemia Cell Lines

Product Type: Human Leukemia Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Other

$1,249.00
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Cell Name: NB-4

The NB-4 cell line was derived from the marrow of a patient with acute promyelocytic leukemia (APL; M3 in the FAB nomenclature) in second relapse in 1989.

  • Product Name
    NB-4
  • Product Type
    Human Leukemia Cell Lines
  • Species
    Human
  • Disease
    Leukemia
  • Product Type
    Human Leukemia Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The NB4 cell line holds significant value in molecular studies involving the t(15;17) chromosomal translocation. Its ability to undergo functional maturation into polynuclear cells following retinoic acid (RA) treatment is another major advantage. This characteristic makes NB4 cells a valuable tool for examining how RA signaling influences on hematopoietic proliferation and differentiation, specifically in terms of genes regulated by RA (either activated or suppressed). Furthermore, the NB4 cell line can be utilized to explore the effects of different maturation inducers, growth factors, chemotherapeutic drugs, and even retroviral vectors, enabling a broader understanding of their impact on cellular processes.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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