Free delivery over $100 Learn more

30 days return period Learn more
SKU: 0605ATC

NEC8 Human Testis Specialized Cells

Tumor Cell Lines > Germ Cell Cancer Cell Lines

Product Type: Human Germ Cell Cancer Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Testis

$1,249.00
Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: NEC8

NEC8 Cell Line is from human; Sex: M; Tissue: testis; Profile: testicular germ cell tumor.

  • Description
    NEC8 is a human embryonal carcinoma cell line derived from a testicular germ cell tumor of a 24-year-old East Asian male patient. This epithelial-like cell line grows adherently in vitro and exhibits high expression of globo-series glycosphingolipids (Gb4 and Gb3), along with cancer stem cell-associated genes such as GADD45β. The cytoplasm of NEC8 cells is characterized by a high abundance of glycogen granules, leading to a strong periodic acid-Schiff (PAS) reaction. Although androgen receptor (AR) expression is relatively low compared to seminoma-derived cells, NEC8 demonstrates tumorigenic potential and primarily consist primarily of embryonal carcinoma cells with the potential for trophoblastic differentiation.
  • Product Name
    NEC8
  • Product Type
    Human Germ Cell Cancer Cell Lines
  • Species
    Human
  • Source Organ
    Testis
  • Product Type
    Human Germ Cell Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    NEC8 plays a crucial role in testicular cancer research, particularly for studying pathogenesis and progression of embryonal carcinoma, a highly malignant subtype of non-seminomatous germ cell tumors. It is frequently used to investigate the molecular mechanisms underlying chemoresistance, aiding in identifying factors responsible for chemotherapeutic resistance in testicular germ cell tumors, offering insights into potential strategies to overcome this resistance. Moreover, NEC8 provides a platform the discovery and evaluation of novel immunotherapy targets, paving the way for the development of innovative, targeted treatment approaches to combat these aggressive malignancies.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 15% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you