SKU: 0519ATC

NFS-70 C10 Mouse Blood Lymphoblasts Cell Line

Tumor Cell Lines > Lymphoma Cell Lines

Product Type: Mouse Lymphocytes Cell Lines

Species: Mouse

Cell Type: Lymphoblasts

Source Organ: Blood

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Cell Name: NFS-70 C10

Mouse Pro-B lymphoblast. Established from a lymphoma produced in an NFS/N mouse by injecting CaS-NS-7 ecotropic MuLV. Cells show pre-B cell markers and appear to be at a very early stage of B-cell differentiation.

  • Description
    NFS-70 C10 is a murine pro-B lymphoblast cell line derived from a lymphoma induced by murine leukemia virus (MuLV) in an NFS/N strain mouse. The cell exhibit typical lymphoblast morphology and grow in suspension culture. This model retains key markers of early B-cell differentiation, including CD5, CD32 (FcγRII), and CD45R (B220), alongside Mac-1 (CD11b), while lacking surface immunoglobulin and Ia antigens. Its immunophenotype (CD5+/CD32+/CD45R+) aligns with pro-B lineage commitment, making it a valuable resource for studying early lymphoid development and hematologic malignancies.
  • Product Name
    NFS-70 C10
  • Product Type
    Mouse Lymphocytes Cell Lines
  • Species
    Mouse
  • Cell Type
    Lymphoblast
  • Source Organ
    Blood
  • Product Type
    Mouse Lymphocytes Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The NFS-70 C10 cell line holds plays a significant role in immunology and retrovirology research, particularly in (murine leukemia virus) MuLV research. It is widely used to investigate B lymphopoiesis and the regulation of lymphoid developement by cytokines. NFS-70 C10 cells enables researchers to explore how specific cytokines influence the B lineage cells differentiation and proliferation, providing insights into immune system development and the mechanisms underlying lymphoid malignancies.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    DMEM + 10% FbS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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