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SKU: 0575ATC

OSC-19 Human Tongue Specialized Cells

Tumor Cell Lines > Head & Neck Cancer Cell Lines

Product Type: Human Tongue Cancer Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Oral Cavity

$1,249.00
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Cell Name: OSC-19

EGF (1-100ng/ml) inhibited the cell growth. The cell could not grow in soft agar but the EGF stimulated colony formation in the soft agar. Human squamous cell carcinoma cell line from tongue tumor with serum-free cell culture.

  • Description
    OSC-19 is a human squamous cell cancer cell line that was originally isolated from the tongue tissue of a 61-year-old East Asian male patient with tongue squamous cell carcinoma. OSC-19 exhibits epithelial-like morphology and adherent culture properties. The characteristic of cultured OSC-19 is lower proliferating activity, lower secretion of laminin, and higher secretion of fibronectin. In addition, OSC-19 is sensitive to EGF treatment. A study utilized a xenotransplantation model to investigate the metastasis mechanism of oral cancer; this work confirmed that OSC-19 is tumorigenic and causes lymph node metastasis.
  • Product Name
    OSC-19
  • Product Type
    Human Tongue Cancer Cell Lines
  • Species
    Human
  • Source Organ
    Tongue
  • Product Type
    Human Tongue Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    OSC-19 holds diverse s in research, serving as an in vitro invasion model to dissect the drivers of invasive behavior. It can be utilized for exploring malignant transformation mechanisms, assessing cytotoxic impacts of compounds on human tongue squamous carcinoma, and dissecting relevant pathways. Moreover, OSC-19 aids in identifying pivotal factors in oral cancer invasion and metastasis, paving the way for novel therapies like siRNA-based approaches, ultimately contributing to advancements in this field.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    DMEM + F12 (1:1)
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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