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SKU: 0513ATC

OVMANA Human Ovary Specialized Cells

Tumor Cell Lines > Ovarian Cancer Cell Lines

Product Type: Human Ovarian Cancer Cell Lines

Species: Human

Cell Type: Other / Specialized Cells

Source Organ: Ovary

$1,249.00
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Cell Name: OVMANA

Ovarian clear cell adenocarcinoma. Cells are transplantable to mouse hypodermis but not to abdominal.

  • Description
    OVMANA is a human ovarian cancer cell line derived from the ovary of a Japanese patient diagnosed with stage IV ovarian clear cell adenocarcinoma (OCCC) who had received cisplatin-based chemotherapy. The cells are epithelial in morphology and can be cultured in RPMI-1640 medium supplemented with 10% fetal bovine serum at 37°C and 5% CO₂. The cells express markers such as HNF1-β, Napsin A. They demonstrate tumorigenic potential, as they are transplantable into mouse hypodermis but not into the abdominal cavity, suggesting site-selective engraftment capacity. OVMANA cells maintain stable growth characteristics under standard culture conditions, making them a valuable model for studying OCCC pathogenesis and drug resistance mechanisms.
  • Product Name
    OVMANA
  • Product Type
    Human Ovarian Cancer Cell Lines
  • Species
    Human
  • Source Organ
    Ovary
  • Product Type
    Human Ovarian Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    OVMANA cells have significant s in cancer research. They enhance our understanding of this rare ovarian cancer subtype, which lacks efficient treatment options, through insights into its molecular mechanisms and genetic alterations. OVMANA cells serve as a model for screening therapeutic compounds, evaluating their ability to induce cell death or autophagy in OCCC. This enables the identification of promising candidates for OCCC treatment. Additionally, these cells aid in investigating the high resistance of OCCC to standard chemotherapy, supporting the development of novel therapies to overcome this resistance and improve patient outcomes. In summary, OVMANA cells contribute to understanding OCCC, facilitate drug testing, and advance research on overcoming chemotherapy resistance in OCCC.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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