Free delivery over $100 Learn more

30 days return period Learn more
SKU: 0232ATC

PC-3 Human Prostate Epithelial Cells

Tumor Cell Lines > Prostate Cancer Cell Lines

Product Type: Human Prostate Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Prostate

$1,249.00
Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: PC-3

The PC-3 was initiated from a bone metastasis of a grade IV prostatic adenocarcinoma from a 62-year-old male Caucasian. The cells exhibit low acid phosphatase and testosterone-5-alpha reductase activities.

  • Description
    PC-3 is a human prostate adenocarcinoma cell line originally derived from a bone metastasis in a 62-year-old Caucasian male with advanced prostate cancer. These cells exhibit epithelial-like morphology with irregular polygonal appearance and adherent culture properties. PC-3 has a highly aneuploid karyotype profile, with chromosomal counts ranging from 58 to 64, falling within the hypertriploid range. The cell line harbors common genetic alterations, including TP53 mutations and PTEN deletion. PC-3 is characterized by the absence of androgen receptor (AR) expression and low prostate-specific antigen (PSA) levels. The cell line is tumorigenic when implanted in SCID mice.
  • Product Name
    PC-3
  • Product Type
    Human Prostate Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Prostate
  • Product Type
    Human Prostate Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The PC-3 cell line is an essential model in prostate cancer research, allowing in-depth investigation into molecular and biochemical pathways involved in advanced-stage prostate cancer. It is widely used to evaluate responses to chemotherapeutic agents and explore mechanisms of drug resistance. Beyond this, PC-3 cells are commonly employed in virology studies particularly in understanding how viral infections interact with immune-related pathwasy in mammalian cells. Their compatibility with transfection techniques also makes them a reliable host for genetic and molecular biology studies. PC-3 cells are particularly valuable for modeling tumor microenvironments and assessing the therapeutic potential of experimental drugs and treatment strategies.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    F12K+10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

    • Visit our support center

      Expert help & advice

    • Check your order status

      Updates & tracking

    • Returns & exchanges

      All you need to know

    • Price-match guarantee

      Our promise to you