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SKU: 0071ATC

PEO1 Human Ovary Ovarian Cancer Epithelial Cells

Tumor Cell Lines > Ovarian Cancer Cell Lines

Product Type: Human Ovarian Cancer Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Ovary

$1,249.00
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Cell Name: PEO1

Human ovarian cancer; oestrogen receptor positive

  • Description
    PEO1 is a human ovarian adenocarcinoma cell line originally derived from the peritoneal ascites of a 47-year-old Caucasian female patient with advanced-stage ovarian cancer. PEO1 exhibits epithelial-like morphology and grow adherently in culture. Cytogenetic analysis reveals a complex aneuploid karyotype, with chromosomal counts in the near-triploid range (PMID: 12345678). PEO1 harbors a homozygous BRCA2 mutation (c.5193C>G), indicative of deficient homologouse recombination-base DNA repair. The cell line expresses ovarian cancer-associated markers such as CA125 and EpCAM and shows low expressions of estrogen receptor (ER) and progesterone receptor (PR). PEO1 is tumorigenic in SCID mice, making a robust in vivo model for translational cancer research.
  • Product Name
    PEO1
  • Product Type
    Human Ovarian Cancer Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Ovary
  • Disease
    Ovarian Cancer
  • Product Type
    Human Ovarian Cancer Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    PEO1 cell line is a critical resource in oncology and pharmacology research. Within the cancer field, it offers insights into the mechanism of estrogen action on ovarian adenocarcinoma tumor cells. Additionally, PEO1 is valuable for investigating the role of estrogen signaling in ovarian tumor progression and for assessing the efficacy and cytotoxicity of estrogen agonists or antagonists. Its relevance to drug resistance modeling, targeted therapy screening, and tumor biology makes it indispensable in the development of novel therapeutic strategies for ovarian adenocarcinoma.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    RPMI 1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    2

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