Free delivery over $100 Learn more

30 days return period Learn more

SKU: 0033APC

Rat Leydig Cells


Primary Cells > Reproductive System Cells

Product Type: Leydig Cells

Species: Rat

Cell Type: Germ Cells

Source Organ: Testis


Regular price $1,249.00

Size

Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Cell Name: Rat Leydig Cells

  • Description
    Rat Leydig Cells (RLCs) are primary interstitial cells harvested from adult rat testes via Percoll-gradient centrifugation. These cells synthesize testosterone through luteinizing hormone (LH) stimulation of the luteinizing hormone/choriogonadotropin receptor (LHCGR), triggering the cyclic adenosine monophosphate–protein kinase A (cAMP–PKA) pathway to upregulate steroidogenic acute regulatory protein (StAR) and cytochrome P450 enzymes. RLCs respond to interleukin‑1α (IL‑1α), growth hormone, and insulin‑like growth factor I (IGF‑I) by enhancing testosterone and dihydrotestosterone production. As a robust in vitro model, RLCs are fundamental for studying steroidogenesis, endocrine control, and Leydig cell biology.
  • Product Name
    Rat Leydig Cells
  • Product Type
    Leydig Cells
  • Species
    Rat
  • Cell Type
    Leydig Cell
  • Source Organ
    Testicles
  • Disease
    Normal
  • Product Type
    Leydig Cells
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    Rat Leydig Cells (RLCs) are employed in steroidogenic regulation research, quantifying testosterone and dihydrotestosterone output after LH, IL‑1α, growth hormone, or IGF‑I stimulation. They are central to toxicology screens assessing inhibitors of steroidogenic enzymes (e.g., CYP11A1) and endocrine disruptors. RLCs also support developmental biology studies on Leydig stem cell maturation and paracrine/endocrine regulation, providing insight into testicular function and repair mechanisms.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement
    Rat Leydig Cells Medium Kit
  • Quality Control
    All cells test negative for mycoplasma, bacteria, yeast, and fungi.
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

Payment & Security

Payment methods

    Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.