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SKU: 0453ATC

RAW-264.7 Mouse Blood Leukemia Immune Cells

Tumor Cell Lines > Leukemia Cell Lines

Product Type: Mouse Lymphocytes Cell Lines

Species: Mouse

Cell Type: Immune Cells

Source Organ: Blood

$1,249.00
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Cell Name: RAW-264.7

RAW-264.7 Cell line was established from a tumor induced by Abelson murine leukemia virus.

  • Description

    RAW 264.7 is a murine macrophage-like cell line derived from a tumor induced by the Abelson leukemia virus in a male BALB/c mouse. These cells exhibit macrophage-like morphology with a distinctive fusiform and polygonal appearance and semi-adherent growth, often forming loose clusters in culture. The karyotype of RAW 264.7 is aneuploid, with a chromosome count of 60 to 66, placing it in the near-triploid range. RAW 264.7 cells express macrophage-specific surface markers such as F4/80 and CD14 and produce high levels of pro-inflammatory cytokines, including TNF-α, IL-1β, in response to stimulation. RAW 264.7 is non-tumorigenic in nude mice. However, it may form transient tumors in certain immunocompromised models at high inoculation doses.
  • Product Name
    RAW-264.7
  • Product Type
    Mouse Lymphocytes Cell Lines
  • Species
    Mouse
  • Cell Type
    Monocyte
  • Source Organ
    Blood
  • Disease
    Leukemia
  • Product Type
    Mouse Lymphocytes Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The RAW-264.7 cell line is a widely used model for studying mouse macrophage biology, particularly in immunology and microbiology research. These cells are instrumental in investigating cellular responses to microbial components, inflammation, and immune signaling. This cell line is also extensively used in osteoclast research, as RAW 264.7 cells can differentiate into osteoclast-like cells (OCLs), providing a reliable in vitro system for studying bone metabolism, osteoclastogenesis, and precursor cell migration toward bone. Additionally, RAW-264.7 cells are a preferred choice as a transfection host due to their suitability, making them a versatile tool for exploring gene expression, signal transduction, and host-pathogen interactions across diverse experimental s.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    DMEM + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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