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SKU: 0352ATC

SK-N-SH Human Bone Marrow Epithelial Cells

Tumor Cell Lines > Nerve Tumor Cell Lines

Product Type: Human Nerve Tumors Cell Lines

Species: Human

Cell Type: Epithelial Cells

Source Organ: Bone Marrow

$1,249.00
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Cell Name: SK-N-SH

The SK-N-SH line was developed by J.L. Biedler and differs from SK-N-MC in that it exhibits a longer doubling time and higher levels of DA - beta - hydroxylase. SK-N-SH has been used as a target cell line in cell mediated cytotoxicity assays.

  • Description
    SK-N-SH is a human neuroblastoma cell line that was originally isolated from metastatic cells found in a 4-year-old female patient’s bone marrow aspirate. SK-N-SH exhibits epithelial-like morphology and adherent culture properties. The stemline karyotype model number of SK-N-SH is 47, with normal chromosomes N9 and N22 being monosomic, and N7 being trisomic. Structural changes form two marker chromosomes, 9q+ and 22q+, with an additional band on one copy of chromosome N7, forming the marker chromosomes described by R.C. Seeger. These cells may have partial translocations on the q arms of chromosomes N9 and N22.
  • Product Name
    SK-N-SH
  • Product Type
    Human Nerve Tumors Cell Lines
  • Species
    Human
  • Cell Type
    Epithelial
  • Source Organ
    Bone Marrow
  • Product Type
    Human Nerve Tumors Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The SK-N-SH cell line is a widely used model in neuroscience research. It facilitates studies on neuronal differentiation, neurodevelopment, and signal transduction. Researchers use these cells to explore the mechanisms of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, and to evaluate neurotoxicity and neuroprotective agents. Their ability to differentiate into neuron-like cells also supports research into brain development and neurological drug discovery.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    DMEM + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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