SKU: 1428APC

WI-38 Human Lung Fibroblasts Cell Line

Primary Cells > Lung & Airway Cells

Product Type: Human Lung Cell Lines

Species: Human

Cell Type: Fibroblasts

Source Organ: Lung

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Cell Name: WI-38

WI-38 Cell Line is from human; Sex: F; Tissue: lung; Morphology: fibroblast-like; Profile: Normal diploid fibroblast with limeted life span. This cell line at around 30 PDL is distributed.

  • Description
    WI-38 is a human fibroblast cell line originally derived from the lung tissue of a 3-month-gestation female fetus of European descent without associated disease. This adherent cell line exhibit fibroblast-like morphology and demonstrates a doubling time of approximately 24 hours under standard culture conditions. Karyotypic analysis confirms a normal diploid complement (46,XX). As the first human diploid cell line approved for vaccine production, it has been instrumental in biomedical research and biomanufacturing. Its susceptibility to a broad range of human viruses, coupled with its genetic stability, has made it instrumental in the production of vaccines against diseases such as rubella, rabies, and adenovirus.
  • Product Name
    WI-38
  • Product Type
    Human Lung Cell Lines
  • Species
    Human
  • Cell Type
    Fibroblast
  • Source Organ
    Lung
  • Disease
    Normal
  • Product Type
    Human Lung Cell Lines
  • Growth Conditions
    37 °C, 5% CO2
  • Application
    The WI-38 cell line has played a pioneering role in vaccine development , serving as the first human cell strain used in production of licensed viral vaccines. It has contribute significantly to the development and manufacturing of vaccines against a spectrum of diseases such as poliomyelitis, measles, mumps, rubella, varicella (chicken pox), herpes zoster, adenovirus, rabies, and Hepatitis A. Moreover, it continues to be a valuable resource for virus propagation, vaccine quality control, and virucide testing, underscores its enduring value in virology and public health research. Beyond its vaccine production utility, WI-38 serves as an reliable transfection host and a model system for studying human cellular aging, senescence, and genome stability, broadening its relevance beyond vaccine s.
  • Size/Quantity
    1 vial
  • Recommended Medium And Supplement

    EMEM + 10% FBS
  • Shipping Conditions
    Dry Ice
  • Storage
    Liquid Nitrogen
  • Biosafety Level
    1

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